Saturday, September 11, 2010

Clinical Trial Onc Meeting

A few weeks ago my regular Onc said we’ve run out of conventional chemotherapy's for me. I pretty well knew I wasn’t done yet. I still feel pretty strong and want to keep up the fight as best I can. So I had asked him to look into clinical trials for me.

So yesterday I had my first appointment with my new clinical trials Onc. He seems like a nice guy and gave me a lot of information in a short amount of time. To help me out, he gave me a 20 page consent form that has most of everything I need to know. The name of the trial is... A Randomized Discontinuations Study of Brivanib alaninate (BMS-582664) versus Placebo in Subjects with Advance Tumours). Yuk huh! What it is … Brivanib is an oral chemotherapy and I’m to take one pill everyday while on the trial. A few of the many known possible side effects are high blood pressure, blood clots, nausea, diarrhea, headache, and fatigue.

The Onc asked me to take a week to think about it. If I choose to participate, I will then have a battery of tests to verify my eligibility for the trial. These tests include an echo-cardiogram, ECG and tons of blood work. I think he mentioned needing a tumor sample too. More yuk.

If everything tested comes back satisfactory, I will be accepted and begin the trial.

Big yayyy.

11 comments:

Sue in Italia/In the Land Of Cancer said...

This sounds promising. Some of the studies have combined it with tamoxifen. It blocks VEGF which makes it difficult for your tumors to get nutrition without a blood supply. Its mechanism is similiar to Avastin. And it is nice that it isn't an infusion. I am keeping my finger crossed for you.

Glenn said...

Daria, I think of you so much. I'm sending you good vibes girl! I've been waiting for the posts to come on where things stood. Keep up the positive spirit angel!!!

kim said...

Daria,
I wish everyone with cancer could wave their wand and go to OZ...
I am excited to hear that there is a possibility of a clinical trial for you--sorry there is the potential for yucky side effects, but as they say--they just have to list 'em--you could be one of the lucky ones and the drugs will work awesome with no side effects.
Continuing to cover you with prayer!

WhiteStone said...

You are one brave lady. I've been reading your blog since soon after my own diagnosis in Jan 2009. Thanks for blogging so well.

nollyposh said...

Good~Luck Hunny xox

Bernie said...

If you agree to take this Daria, can you cancel out if the side effects get to bad.....I don't like to think of you hurting and feelig miserable.....this may just be the miracle we have all been praying for though, you have to try it.
Good luck my friend....:-)Hugs

Daria said...

Bernie, I'm sure I can cancel anytime. Regarding the side effects ... I think I'll be ok with the regular side effects, nausea, diarrhea, headaches, etc ... they are par for the course.

Chez said...

Love your positive approach to life [and side effects] Daria.

Dee said...

Here's hoping you are eligible form the trial. Have you tried Avastin? I can't remember. I may be starting that sometime down the road, although I know it has a checkered record.

Daria said...

Hi Dee ... I haven't tried Avastin.

DebMarie said...

Oh my gosh Daria, you go girl. Missing you on Twitter!